Impact of continuous glucose monitoring on hospitalizations and glucose control in people with type 2 diabetes: real-world analysis


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Impact of continuous glucose monitoring on hospitalizations and glucose control in people with type 2 diabetes: real-world analysis

Aim: The real-world benefits of continuous glucose monitoring (CGM) in the broad type 2 diabetes (T2D) population are not well studied. Our study evaluated the impact of CGM use on health care resource utilization over 12 months in adults with T2D. Materials and

Methods: This retrospective cohort analysis used Optum's de-identified Market Clarity data of >79 million people to evaluate CGM use in people with T2D who were treated with non-insulin (NIT), basal insulin (BIT) and prandial insulin therapy (PIT). The primary outcomes were changes in all-cause hospitalizations, acute diabetes-related hospitalizations and acute diabetes-related emergency room visits during the 6- and 12-month post-index period following transition from blood glucose monitoring to CGM. A pre-specified subgroup analysis assessed glucose control and medication changes among people with T2D over 1 year.

Results: The analysis included 74 679 adults with T2D ( NIT; n = 25 269), (BIT; n = 16 264) and (PIT; n = 33 146). Significant reductions in all-cause hospitalizations, acute diabetes-related hospitalizations and acute diabetes-related emergency room visits were observed in the 6-month post-index period that were sustained during the 6–12 month post-index period (NIT, −10.1%, −31.0%, −30.7%; BIT, −13.9%, −47.6%, −28.2%; and PIT, −22.6%, −52.7%, −36.6%, respectively). A subgroup analysis of 6030 people showed mean glycated haemoglobin reductions at approximately 3 months, which were also sustained throughout the post-index period: NIT, −1.1 (0.05)%; BIT, −1.1 (0.06)%; and PIT, −0.9 (0.04)%, p < 0.0001. Conclusions: CGM use in real-life across different therapeutic regimens in adults with T2D was associated with reductions in health care resource utilization with improved glucose control over 1 year. © 2024 The Author(s). Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

Authors : Garg S.K.; Hirsch I.B.; Repetto E.; Snell-Bergeon J.; Ulmer B.; Perkins C.; Bergenstal R.M.

Source : John Wiley and Sons Inc

Article Information

Year 2024
Type Article
DOI 10.1111/dom.15866
ISSN 14628902
Volume 26

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