Here are the Healthcare utilization, mortality, and cardiovascular events following GLP1-RA initiation in chronic kidney disease journals presenting the latest research across various disciplines. From social sciences to technology, each article is expected to provide valuable insights to our readers.
Healthcare utilization project, utilization management in healthcare, healthcare utilization by state, healthcare utilization and cost, health care utilization model, health service utilization rate, healthcare utilization questionnaire, utilization of healthcare services.
Healthcare utilization, mortality, and cardiovascular events following GLP1-RA initiation in chronic kidney disease
Treatment with glucagon-like peptide-1 receptor agonists (GLP1-RA) in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) may attenuate kidney disease progression and cardiovascular events but their real-world impact on healthcare utilization and mortality in this population are not well-defined. Here, we emulate a clinical trial that compares outcomes following initiation of GLP1-RA vs Dipeptidyl peptidase-4 inhibitors (DPP4i), as active comparators, in U.S. veterans aged 35 years of older with moderate to advanced CKD during fiscal years 2006 to 2021. Primary outcome was rate of acute healthcare utilization. Secondary outcomes were all-cause mortality and a composite of acute cardiovascular events. After propensity score matching (16,076 pairs) and 2.2 years mean follow-up duration, use of GLP1-RA in patients with moderate to advanced CKD was associated with lower annual rate of acute healthcare utilization and all-cause mortality. There was no significant difference in acute cardiovascular events. © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024.
Authors : Zhang S.; Sidra F.; Alvarez C.A.; Kinaan M.; Lingvay I.; Mansi I.A.
Source : Nature Research
Article Information
| Year | 2024 |
| Type | Article |
| DOI | 10.1038/s41467-024-54009-3 |
| ISSN | 20411723 |
| Volume | 15 |
You can download the article here
If You have any problem, contact us here