Here are the Is metformin safe in pregnancy: a focus on offspring outcomes journals presenting the latest research across various disciplines. From social sciences to technology, each article is expected to provide valuable insights to our readers.
Is metformin safe in pregnancy announcement, why is metformin dangerous, is metformin safe in pregnancy a focus fireplace, is metformin safe, is metformin a good or bad drug, is metformin safe in pregnancy a focus on planning, is metformin safe in early pregnancy, is metformin safe in pregnancy a focus on offspring tv, is metformin safe for diabetics.
Is metformin safe in pregnancy: a focus on offspring outcomes
Introduction: Metformin has been part of treatment algorithms for type 2 diabetes mellitus (T2DM) for decades. While it has formal approval in the U.S.A. for treatment of T2DM, it is used off-label in gestational diabetes mellitus (GDM), polycystic ovarian syndrome (PCOS), and ovarian hyperstimulation prevention. Its role as an insulin sensitizer has made it an attractive therapeutic to address the insulin resistance seen in these syndromes. In 2022, the European Union approved metformin as the only oral antidiabetic medication for diabetes in pregnancy. While its safety and benefits for the mother are well documented, it does cross the placenta with plasma concentrations comparable between mother and child at delivery. Areas covered: This special report will focus on major randomized control trials investigating metformin use in pregnancies impacted by PCOS, GDM, T2DM, and obesity and their offspring follow-up trials. Expert Opinion: For the mother, metformin can be benefici al, with reduction in insulin therapeutic burden, weight gain, hypoglycemia and in certain situations, pre-eclampsia. For the neonate, benefits may include reduction in hypoglycemia and no increased risk of congenital anomalies. It is the long-term data in the offspring that remains unknown with some areas of concerns (SGA, altered anthropometrics) requiring continued research. © 2024 Informa UK Limited, trading as Taylor & Francis Group.
Authors : Malek R.; Davis S.N.
Source : Taylor and Francis Ltd.
Article Information
| Year | 2025 |
| Type | Article |
| DOI | 10.1080/14740338.2024.2424410 |
| ISSN | 14740338 |
| Volume | 24 |
You can download the article here
If You have any problem, contact us here