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Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies
Aims Type 2 diabetes (T2D) is more common in certain ethnic groups. This systematic review compares mortality risk between people with T2D from different ethnic groups and includes recent larger studies. Methods We searched nine databases using PRISMA guidelines (PROSPERO CRD42022372542). We included community-based prospective studies among adults with T2D from at least two different ethnicities. Two independent reviewers undertook screening, data extraction and quality assessment using the Newcastle-Ottawa Scale. The primary outcome compared allcause mortality rates between ethnic groups (hazard ratio (HR) with 95% confidence intervals). Results From 30,825 searched records, we included 13 studies (7 meta-analysed), incorporating 573,173 T2D participants; 12 were good quality. Mortality risk was lower amongst people with T2D from South Asian [HR 0.68 (0.65–0.72)], Black [HR 0.82 (0.77–0.87)] and Chinese [HR 0.57 (0.46–0.70)] ethnicity compared to people of White ethni city. Narrative synthesis corroborated these findings but demonstrated that people of indigenous MÄori ethnicity had greater mortality risk compared to European ethnicity. Conclusions People with T2D of South Asian, Black and Chinese ethnicity have lower all-cause mortality risk than White ethnicity, with MÄori ethnicity having higher mortality risk. Factors explaining mortality differences require further study, including understanding complication risk by ethnicity, to improve diabetes outcomes. © 2025 Chaudhry et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Authors : Chaudhry U.A.R.; Fortescue R.; Bowen L.; Woolford S.J.; Knights F.; Cook D.G.; Harris T.; Critchley J.
Source : Public Library of Science
Article Information
| Year | 2025 |
| Type | Article |
| DOI | 10.1371/journal.pone.0314318 |
| ISSN | 19326203 |
| Volume | 20 |
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